Microfluidic jet injection for delivering macromolecules into cells.

نویسندگان

  • A Adamo
  • O Roushdy
  • R Dokov
  • A Sharei
  • K F Jensen
چکیده

We present a microfluidic based injection system designed to achieve intracellular delivery of macromolecules by directing a picoliter-jet of a solution towards individual cells. After discussing the concept, we present design specification and criteria, elucidate performance and discuss results. The method has the potential to be quantitative and high throughput, overcoming limitations of current intracellular delivery protocols.

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عنوان ژورنال:
  • Journal of micromechanics and microengineering : structures, devices, and systems

دوره 23  شماره 

صفحات  -

تاریخ انتشار 2013